EIF5A2

Alternative Names: Eukaryotic translation initiation factor 5A-2, Eukaryotic initiation factor 5A isoform 2, EIF-5A-2, EIF5A2, eIF-5A-2, eIF5AII

EIF5A2 is a crucial protein involved in cellular polyamine homeostasis. It belongs to the eukaryotic initiation factor 5A subfamily and plays a role in facilitating the formation of the first peptide bond during protein synthesis. Notably, EIF5A2 is unique among eukaryotic proteins as it contains a hypusine residue, which is a post-translational modification of a lysine by the addition of a butylamino group.

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  • Sku: PSB-pro-846-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Eukaryotic Translation Initiation Factor 5A2 (eIF5A2) is a protein involved in the initiation of protein synthesis in eukaryotic cells. Belonging to the eIF5A family, it plays a role in the delivery of the initiator methionyl-tRNA to the ribosome during translation. With a molecular weight of approximately 18 kDa, eIF5A2 is an essential component of the translation machinery, facilitating the accurate and efficient synthesis of proteins. Its functional significance lies in its ability to regulate cell proliferation, differentiation, and apoptosis, making it a subject of interest in various physiological and pathological processes.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation EIF5A2 Human solution containing 20mM Tris-HCl pH-8 & 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MADEIDFTTG DAGASSTYPM QCSALRKNGF VVLKGRPCKI VEMSTSKTGK HGHAKVHLVG IDIFTGKKYE DICPSTHNMD VPNIKRNDYQ LICIQDGYLS LLTETGEVRE DLKLPEGELG KEIEGKYNAG EDVQVSVMCA MSEEYAVAIK PCK.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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EIF5A2

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