EIF4EBP3

Alternative Names: Eukaryotic translation initiation factor 4E-binding protein 3, EIF4EBP3, eIF4E-binding protein 3, 4E-BP3, 4EBP3.

EIF4EBP3 is a member of the EIF4EBP protein family. These proteins bind to eukaryotic initiation factor 4E (eIF4E) and control its formation into EIF4F, a translation initiation factor that recognizes the mRNA cap structure.

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  • Sku: PSB-pro-2054-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Eukaryotic Translation Initiation Factor 4E-Binding Protein 3 (4E-BP3) is a member of the eukaryotic translation initiation factor 4E-binding protein family. With a molecular weight of approximately X kDa, 4E-BP3 plays a regulatory role in protein synthesis by binding to the eukaryotic translation initiation factor 4E (eIF4E). This interaction inhibits translation initiation, thereby modulating the efficiency of mRNA translation. Understanding the function and regulation of 4E-BP3 contributes to the broader comprehension of protein synthesis control mechanisms in eukaryotic cells.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The EIF4EBP3 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMSTSTSC PIPGGRDQLP DCYSTTPGGT LYATTPGGTR IIYDRKFLLE CKNSPIARTP PCCLPQIPGV TTPPTAPLSK LEELKEQETE EEIPDDAQFE MDI.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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EIF4EBP3

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