EGFR Sf9, Active

Alternative Names: Epidermal growth factor receptor, Receptor tyrosine-protein kinase ErbB-1, ERBB, ERBB1, EGFR, mENA, EC 2.7.10.1

The EGF receptor (EGF R) subfamily consists of four types of receptor tyrosine kinases: EGF R (also known as HER1, ErbB1 or ErbB), ErbB2 (Neu, HER-2), ErbB3 (HER-3), and ErbB4 (HER-4). These proteins are located on the cell membrane, with an extracellular domain for ligand binding and a cytoplasmic domain containing a tyrosine kinase domain. The human EGF R gene encodes a protein with specific domains and regions. EGF R can bind various ligands like EGF and induce cell signaling by dimerization with other receptors. EGF R signaling influences cell behaviors like proliferation and apoptosis, and is implicated in cancer development.

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  • Sku: PSB-pka-335-1µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Epidermal Growth Factor Receptor-Sf9, Active is a protein belonging to the epidermal growth factor receptor family. With a molecular weight of approximately 170 kDa, this protein plays a key role in cell growth and proliferation. It is commonly used in research studies to study signaling pathways and potential therapeutic targets related to cancer and other diseases.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Sf9 - Baculovirus cells
Purity
Activity
Determination of Km value by Filter binding assay MAFC membrane.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation EGFR in 50mM HEPES pH 7.5, 100mM NaCl, 5mM DTT, 15mM reduced glutathione and 20% glycerol.

*For Research Use Only

Notes

Specific Activity: 30 pmol/µgxmin

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

Check Uniprot Link

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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EGFR Sf9, Active

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