EGF, (Leu 21)

Alternative Names: EGF, URG, Urogastrone

Epidermal growth factor (EGF) is a powerful factor that influences the differentiation of specific cells in living organisms. It is also a potent stimulator of cell division for various types of cultured cells from both ectodermal and mesodermal origins. EGF is believed to be present as a membrane-bound molecule and is cleaved to produce a 53-amino acid peptide hormone that promotes cell division. In addition, EGF promotes the growth of epidermal and epithelial tissues both in vivo and in vitro, as well as certain fibroblasts in cell culture.

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  • Sku: PSB-cyt-466-20µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Epidermal Growth Factor 21-Leu is a synthetic version of the human protein Epidermal Growth Factor 21 (EGF21) with a leucine substitution. Belonging to the family of epidermal growth factors, this protein plays a significant role in regulating cell growth, proliferation, and differentiation. With a molecular weight of approximately X kDa, Recombinant Human EGF21-Leu exhibits potential therapeutic applications in various fields, including wound healing, tissue repair, and metabolic disorders. Its precise and controlled administration holds promise for enhancing medical interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 98% by SDS-PAGE
Activity
The ED50, calculated by the dose-dependant proliferation of MDCK cells is < 10ng/ml concentration corresponding to a Specific Activity of 100,000IU/mg. The ED50, calculated by the dose-dependant proliferation of MDCK cells is < 10ng/ml concentration corresponding to a Specific Activity of 100,000IU/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The protein was lyophilized from a concentrated (1mg/ml) solution with no additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

The sequence of the first five N-terminal amino acids was determined and was found to be Asn-Ser-Asp-Ser-Glu.

Storage Instruction

Lyophilized Epidermal Growth Factor 21 Leu although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution EGF 21-Leu should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Epidermal Growth Factor 21-Leu in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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EGF, (Leu 21)

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