Product Description

Recombinant Pyrococcus Fruriosus Deoxyuridine Triphosphatase (PFDT) is an enzyme that plays a crucial role in DNA replication and repair processes. Belonging to the family of deoxyuridine triphosphatases, PFDT is responsible for maintaining the fidelity of DNA synthesis by hydrolyzing deoxyuridine triphosphate (dUTP) into deoxyuridine monophosphate (dUMP) and inorganic pyrophosphate. With a molecular weight of approximately 25 kDa, this enzyme acts as a safeguard against the incorporation of dUTP into DNA, which can lead to mutagenesis and genomic instability. By precisely regulating dUTP levels, PFDT contributes to the overall stability and accuracy of DNA replication, making it a vital component in cellular processes.

Current Lead Time

7-14 Days

Product Specifications

*For Research Use Only

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
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