DTYMK

Alternative Names: Not Available

DTYMK plays a crucial role in pyrimidine metabolism by catalyzing the conversion of dTMP to dTDP. This conversion is ATP-dependent and dTDP is an essential building block for DNA. DTYMK's involvement in the creation of dTDP makes it vital for DNA synthesis and is believed to play a role in cell cycle progression and cell growth.

Skip to product information
  • Sku: PSB-pka-005-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
 per 
Shipping calculated at checkout.

Contact us directly for international purchases.

Title

Product Details

Product Description

Recombinant Human Deoxythymidylate Kinase is an enzyme involved in the synthesis of DNA. Belonging to the kinase family, it plays a crucial role in catalyzing the phosphorylation of deoxythymidine monophosphate (dTMP) to produce deoxythymidine diphosphate (dTDP). With a molecular weight of approximately X kDa, this enzyme is essential for maintaining the balance of nucleotide pools within cells, ensuring accurate DNA replication and repair processes. Its significance lies in its ability to regulate the availability of dTTP, a key building block required for DNA synthesis, making Recombinant Human Deoxythymidylate Kinase a vital component in cellular proliferation and genetic stability.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation DTYMK protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 20% glycerol, 2mM DTT and 0.1M NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MAARRGALIV LEGVDRAGKS TQSRKLVEAL CAAGHRAELL RFPERSTEIG KLLSSYLQKK SDVEDHSVHL LFSANRWEQV PLIKEKLSQG VTLVVDRYAF SGVAFTGAKE NFSLDWCKQP DVGLPKPDLV LFLQLQLADA AKRGAFGHER YENGAFQERA LRCFHQLMKD TTLNWKMVDA SKSIEAVHED IRVLSEDAIR TATEKPLGEL WK.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

View full details

DTYMK

SUBHEADING

Recently viewed products