DPP4

Alternative Names: CD26, CD26 antigen, T-cell activation antigen CD26, Adenosine deaminase complexing protein 2, ADCP2, Dipeptidyl peptidase IV, DPPIV, DPP IV, DPP4, Dipeptidyl peptidase 4, TP103, ADABP

DPP4, also known as adenosine deaminase complexing protein-2 and T-cell activation antigen CD26, is a serine exopeptidase expressed on most cell types. This enzyme cleaves X-proline dipeptides from the N-terminus of polypeptides and is involved in t-cell activation, signaling pathways, apoptosis, tumor biology, and glucose metabolism. DPP4 has at least 63 substrates, including growth factors, chemokines, and neuro peptides. Notably, DPP4 plays a crucial role in glucose metabolism by cleaving incretins like GIP and GLP-1.

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  • Sku: PSB-enz-375-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Dipeptidyl-Peptidase 4, also known as DPP4, is a member of the serine protease family. This enzyme is responsible for cleaving dipeptides from the N-terminus of proteins and peptides. With a molecular weight of approximately 110 kDa, Recombinant Human Dipeptidyl-Peptidase 4 plays a role in various biological processes, including glucose metabolism and immune response regulation.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Insect Cell
Purity 95% by SDS-PAGE
Activity
>200 Units/mg. >200 Units/mg.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
85.4 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation DPP4 is formulated in 20mM Tris-HCl buffer pH-8, 100mM NaCl, 1mM EDTA and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ADPSRKTYTL TDYLKNTYRL KLYSLRWISD HEYLYKQENN ILVFNAEYGN SSVFLENSTF DEFGHSINDY SISPDGQFIL LEYNYVKQWR HSYTASYDIY DLNKRQLITE ERIPNNTQWV TWSPVGHKLA YVWNNDIYVK IEPNLPSYRI TWTGKEDIIY NGITDWVYEE EVFSAYSALW WSPNGTFLAY AQFNDTEVPL IEYSFYSDES LQYPKTVRVP YPKAGAVNPT VKFFVVNTDS LSSVTNATSI QITAPASMLI GDHYLCDVTW ATQERISLQW LRRIQNYSVM DICDYDESSG RWNCLVARQH IEMSTTGWVG RFRPSEPHFT LDGNSFYKII SNEEGYRHIC YFQIDKKDCT FITKGTWEVI GIEALTSDYL YYISNEYKGM PGGRNLYKIQ LSDYTKVTCL SCELNPERCQ YYSVSFSKEA KYYQLRCSGP GLPLYTLHSS VNDKGLRVLE DNSALDKMLQ NVQMPSKKLD FIILNETKFW YQMILPPHFD KSKKYPLLLD VYAGPCSQKA DTVFRLNWAT YLASTENIIV ASFDGRGSGY QGDKIMHAIN RRLGTFEVED QIEAARQFSK MGFVDNKRIA IWGWSYGGYV TSMVLGSGSG VFKCGIAVAP VSRWEYYDSV YTERYMGLPT PEDNLDHYRN STVMSRAENF KQVEYLLIHG TADDNVHFQQ SAQISKALVD VGVDFQAMWY TDEDHGIASS TAHQHIYTHM SHFIKQCFSL PHHHHHH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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DPP4

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