DNAJC19

Alternative Names: TIM14, TIMM14, Pam18, Mitochondrial import inner membrane translocase subunit TIM14, DnaJ homolog subfamily C member 19, DNAJC19.

DNAJC19 is involved in the transport of transit peptide-containing proteins from the inner cell membrane to the mitochondrial matrix. It is a single-pass membrane protein with a J domain and is found in the inner membrane of the mitochondrion. It is expressed throughout the body and functions as part of the mitochondrial DNAJC19 complex, which is responsible for the ATP-dependent translocation of specific proteins from the inner mitochondrial membrane to the mitochondrial matrix. Mutations in the DNAJC19 gene cause 3-methylglutaconic aciduria type 5 (MGA5), also known as dilated cardiomyopathy with ataxia (DCMA).

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  • Sku: PSB-hsp-039-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human DnaJ (Hsp40) Homolog, Subfamily C, Member 19 is a protein belonging to the DnaJ/Hsp40 family. With a molecular weight of approximately X kilodaltons, this protein plays a role in cellular processes by assisting in protein folding, assembly, and disassembly. It functions as a co-chaperone, interacting with heat shock proteins to regulate their activity. Recombinant Human DnaJ (Hsp40) Homolog, Subfamily C, Member 19 is involved in various cellular pathways, making it a subject of interest in scientific research.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
15.1 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The DNAJC19 solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol, 2mM DTT and 0.1M NaCl.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMGRY VLQAMKHMEP QVKQVFQSLP KSAFSGGYYR GGFEPKMTKR EAALILGVSP TANKGKIRDA HRRIMLLNHP DKGGSPYIAA KINEAKDLLE GQAKK.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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DNAJC19

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