DKK3 HEK
Alternative Names: Dickkopf 3 homolog (Xenopus laevis), dickkopf-related protein 3, Dkk-3, regulated in glioma, REIC, RIG, RIG-like 7-1, RIG-like 5-6.
- Sku: PSB-pro-1638-2µg
- Vendor: ProSpec-Tany
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Product Description
Recombinant Human Dickkopf-Related Protein 3, HEK, is a bioengineered protein derived from human cells, specifically the HEK293 cell line. Belonging to the Dickkopf (DKK) family, this protein plays a significant role in regulating the Wnt signaling pathway, which is crucial for embryonic development and tissue homeostasis. With a molecular weight of approximately 27 kilodaltons, Recombinant Human Dickkopf-Related Protein 3, HEK, exhibits potent inhibitory activity on Wnt signaling by binding to the Wnt co-receptor LRP5/6, thereby blocking the interaction between Wnt ligands and the Frizzled receptor. This recombinant protein serves as a valuable tool in various research applications aiming to study the intricate mechanisms of Wnt signaling and its implications in disease progression.
Current Lead Time
7-14 Days
Product Specifications
|
Species |
Human |
| Expression System | HEK 293 |
| Purity | 95% by SDS-PAGE |
|
Activity |
Not Available |
| Activity Assay | |
| Animal Component Free (ACF) | No |
|
Molecular Weight |
N/A |
| Structure | Monomer |
|
Endotoxin Concentration |
Not Available |
| Purification Method | Not Available |
|
Form |
Lyophilized |
| Formulation | DKK3 was lyophilized from a 0.2µM filtered solution of 20mM PB and 150mM NaCl, pH 7.2. |
*For Research Use Only
If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation.
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DKK3 HEK