DECR1

Alternative Names:

Acid Phosphatase 5, Tartrate Resistant, Tartrate-Resistant Acid ATPase, Human Purple Acid Phosphatase, EC 3.1.3.2, TrATPase, Tartrate-Resistant Acid Phosphatase Type 5, Tartrate-Resistant Acid Phosphatase 5a, Tartrate-Resistant Acid Phosphatase 5b, Tartrate-Resistant Acid Phosphatase, Type 5 Acid Phosphatase, TRACP5a, TRACP5b, TR-AP, HPAP, TRAP, ACP5.

ACP5, also known as tartrate-resistant acid phosphatase type 5, is an iron-containing glycoprotein involved in dephosphorylating osteopontin and bone sialoprotein. It catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. ACP5 expression appears to increase in certain pathological conditions like Gaucher and Hodgkin diseases, hairy cell leukemia, B-cell leukemia, and T-cell leukemia. Unlike other acid phosphatases, ACP5 is not inhibited by L(+)-tartrate and is considered the most basic form.

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  • Sku: PSB-enz-102-2µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human 2,4-Dienoyl CoA Reductase 1 is an enzyme that plays a key role in fatty acid metabolism. Belonging to the oxidoreductase family, this protein is responsible for catalyzing the reduction of 2,4-dienoyl-CoA to yield 3-trans-enoyl-CoA. With a molecular weight of approximately 33 kDa, Recombinant Human 2,4-Dienoyl CoA Reductase 1 is essential for maintaining proper lipid homeostasis within cells.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System Sf9 - Baculovirus cells
Purity 90.0 % by SDS-PAGE
Activity
 Specific activity is >10,000 units/mg, and is defined as the amount of enzyme that hydrolyze 1.0 nmoles of p-nitrophenyl phosphate (pNPP) per minute at pH 5.0 at 37°C.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 34.3 kDa
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation ACP5 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ATPALRFVAV GDWGGVPNAP FHTAREMANA KEIARTVQIL GADFILSLGD NFYFTGVQDI NDKRFQETFE DVFSDRSLRK VPWYVLAGNH DHLGNVSAQI AYSKISKRWN FPSPFYRLHF KIPQTNVSVA IFMLDTVTLC GNSDDFLSQQ PERPRDVKLA RTQLSWLKKQ LAAAREDYVL VAGHYPVWSI AEHGPTHCLV KQLRPLLATY GVTAYLCGHD HNLQYLQDEN GVGYVLSGAG NFMDPSKRHQ RKVPNGYLRF HYGTEDSLGG FAYVEISSKE MTVTYIEASG KSLFKTRLPR RARP.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
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References

Not Available
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DECR1
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