DDR2

Alternative Names: Discoidin domain-containing receptor 2, DDR2, MIG20a, NTRKR3, TKT, TYR010, Discoidin Domain Receptor Tyrosine Kinase 2, CD167 antigen-like family member B, Discoidin domain-containing receptor tyrosine kinase 2, Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, Tyrosine-protein kinase TYRO10, CD_antigen: CD167b.

Recombinant Human Discoidin Domain Receptor Tyrosine Kinase 2, also known as DDR2, is a member of the receptor tyrosine kinase family. This protein plays a significant role in cell adhesion and migration processes. With a molecular weight of approximately 97 kDa, DDR2 is involved in collagen binding and signaling pathways related to tissue development and remodeling. Its activation triggers downstream signaling cascades, contributing to cellular responses such as proliferation and differentiation. Understanding the functions and mechanisms of DDR2 can provide valuable insights into various physiological and pathological processes.

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  • Sku: PSB-pka-329-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Discoidin Domain Receptor Tyrosine Kinase 2, also known as DDR2, is a member of the receptor tyrosine kinase family. This protein plays a significant role in cell adhesion and migration processes. With a molecular weight of approximately 97 kDa, DDR2 is involved in collagen binding and signaling pathways related to tissue development and remodeling. Its activation triggers downstream signaling cascades, contributing to cellular responses such as proliferation and differentiation. Understanding the functions and mechanisms of DDR2 can provide valuable insights into various physiological and pathological processes.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Sf9 - Baculovirus cells
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
43.7 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation DDR2 solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

KAQVNPAICR YPLGMSGGQI PDEDITASSQ WSESTAAKYG RLDSEEGDGA WCPEIPVEPD DLKEFLQIDL HTLHFITLVG TQGRHAGGHG IEFAPMYKIN YSRDGTRWIS WRNRHGKQVL DGNSNPYDIF LKDLEPPIVA RFVRFIPVTD HSMNVCMRVE LYGCVWLDGL VSYNAPAGQQ FVLPGGSIIY LNDSVYDGAV GYSMTEGLGQ LTDGVSGLDD FTQTHEYHVW PGYDYVGWRN ESATNGYIEI MFEFDRIRNF TTMKVHCNNM FAKGVKIFKE VQCYFRSEAS EWEPNAISFP LVLDDVNPSA RFVTVPLHHR MASAIKCQYH FADTWMMFSE ITFQSDAAMY NNSEALPTSP MAPTTYDPML KVDDSNTRLE HHHHHH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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DDR2

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