Cyclosporin-A

Alternative Names: Not Available

Cyclosporin A is a natural peptide that is used in the medical field as an immunosuppressant. It is effective in treating autoimmune and inflammatory disorders and preventing organ rejection after transplantation. Cyclosporin works by inhibiting the function of T lymphocytes, which play a key role in causing inflammation. Unlike other immunosuppressive agents, Cyclosporin A does not suppress the activity of other blood cells or cause bone marrow suppression. It has a fast onset of action. However, there is a concern of kidney damage caused by Cyclosporin A, and oxidative stress is thought to be a potential cause.

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  • Sku: PSB-pro-408-1gram
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Cyclosporin-A is a potent immunosuppressive drug widely used in organ transplantation to prevent rejection. Belonging to the cyclic peptide family, it possesses a molecular weight of approximately 1,200 Daltons. Cyclosporin-A works by inhibiting the activation of T-cells, a crucial component of the immune system, thereby suppressing the immune response against transplanted organs. This pharmaceutical compound has revolutionized the field of transplantation medicine, ensuring improved patient outcomes and graft survival rates.

Current Lead Time

7-14 Days

Product Specifications

Species
Fungus
Expression System Beauveria Nivea
Purity 99.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation The Cyclosporin-A was lyophilized from a concentrated (1mg/ml) solution with no additives.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Lyophilized Cyclosporin A although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Cyclosporin A should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized Cyclosporin-A in anhydrous ethanol R at a concentration of 50mg/ml.

References

Not Available

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Cyclosporin-A

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