CXCL17 His

Alternative Names: Not Available

DMC/CXCL17/VCC1 is a secreted molecule similar in size and structure to chemokines CXCL8/IL8 and CXCL14/BRAK. It is produced by airway and intestinal epithelium and attracts quiescent monocytes and dendritic cells, but not activated ones. CXCL17's expression is increased in endothelial cells during tube formation in vitro, and its expression is correlated with angiogenesis-related chemokines in lung, breast, and esophageal tumors. The mature Rat CXCL17 shares high amino acid sequence identity with mouse and human CXCL17.

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  • Sku: PSB-chm-024-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human VEGF Co-regulated Chemokine 1, His Tag is a protein belonging to the chemokine family, specifically designed for research purposes. With a molecular weight of approximately 8.6 kDa, this protein plays a role in regulating immune responses and inflammation. The addition of the His Tag allows for easy purification and detection in laboratory settings. This recombinant protein is commonly used in studies related to angiogenesis, cancer, and inflammatory diseases.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
13.7 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CXCL17 protein solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MSSLNPGVAR GHRDRGQASR RWLQEGGQEC ECKDWFLRAP RRKFMTVSGL PKKQCPCDHF KGNVKKTRHQ RHHRKPNKHS RACQQFLKQC QLRSFALPL.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CXCL17 His

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