CTHRC1 HEK

Alternative Names: Protein NMTC1, Collagen Triple Helix Repeat Containing 1, CTHRC1.

Collagen triple helix repeat-containing protein 1 (CTHRC1) is a glycosylated 28kDa protein that negatively regulates collagen matrix deposition. It is highly conserved from lower chordates to mammals and is closely associated with calcified tissues and cartilaginous matrix. However, CTHRC1 is not found in endothelial cells. Qualitatively, CTHRC1 can be detected in the plasma of healthy individuals, with significantly higher levels observed during pregnancy, in diabetes, in inflammatory and infectious conditions, and in subjects with acute myeloid leukemia. Interestingly, CTHRC1 plasma levels do not increase in subjects with solid cancers. CTHRC1 also plays a role in hormone regulation, affecting lipid storage and cellular glycogen levels. The deletion of the CTHRC1 gene in mice leads to the formation of fatty liver (steatosis), while inactivation of the gene results in low bone mass.

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  • Sku: PSB-pro-2028-2µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human Collagen Triple Helix Repeat Containing 1 (HEK) is a protein belonging to the collagen family. With a weight of approximately X kDa, it plays a significant role in various biological processes. This protein is synthesized through recombinant DNA technology, allowing for precise control over its production and purification. HEK is involved in maintaining the structural integrity of tissues, providing mechanical support, and facilitating cell adhesion. Its versatile nature and potential applications make it a subject of interest in research and development within the scientific community.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System HEK 293
Purity 95% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
 N/A
Structure Monomer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Lyophilized
Formulation CTHRC1 was filtered (0.4µm) and lyophilized in phosphate buffered saline pH 7.5.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

SEIPKGKQKA QLRQREVVDL YNGMCLQGPA GVPGRDGSPG ANGIPGTPGI PGRDGFKGEK GECLRESFEE SWTPNYKQCS WSSLNYGIDL GKIAECTFTK MRSNSALRVL FSGSLRLKCR NACCQRWYFT FNGAECSGPL PIEAIIYLDQ GSPEMNSTIN IHRTSSVEGL CEGIGAGLVD VAIWVGTCSD YPKGDASTGW NSVSRIIIEE LPK HHHHHH.

Storage Instruction

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

Sample Prep Instruction

It is recommended to add deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. CTHRC1 is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

References

Not Available
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CTHRC1 HEK
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