CTBP1

Alternative Names: EC 1.1.1, MGC104684, BARS, CTBP1, C-terminal-binding protein 1, CTBP.

CTBP1 is involved in maintaining the balance between tubular and stacked structures in the Golgi complex. It also plays a role in brown adipose tissue differentiation and has dehydrogenase activity. CTBP1 binds to the C-terminus of adenovirus E1A proteins and acts as a transcriptional repressor during cellular proliferation. It can dimerize with CTBP2 and interact with a polycomb group protein complex, which is involved in gene expression regulation during development.

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  • Sku: PSB-pro-796-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human C-Terminal Binding Protein 1 (CTBP1) is a protein that plays a crucial role in various cellular processes. Belonging to the C-terminal binding protein family, CTBP1 is involved in transcriptional repression, cell cycle regulation, and apoptosis. With a molecular weight of approximately 49 kilodaltons, this protein functions as a transcriptional co-repressor by binding to specific DNA sequences and recruiting histone deacetylases to modify chromatin structure. Understanding the role and function of Recombinant Human C-Terminal Binding Protein 1 is of significant interest in various fields of scientific research.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The CTBP1 protein solution contains 20mM Tris-HCl, pH-8, 100mM NaCl and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHLLNKG LPLGVRPPIM NGPLHPRPLV ALLDGRDCTV EMPILKDVAT VAFCDAQSTQ EIHEKVLNEA VGALMYHTIT LTREDLEKFK ALRIIVRIGS GFDNIDIKSA GDLGIAVCNV PAASVEETAD STLCHILNLY RRATWLHQAL REGTRVQSVE QIREVASGAA RIRGETLGII GLGRVGQAVA LRAKAFGFNV LFYDPYLSDG VERALGLQRV STLQDLLFHS DCVTLHCGLN EHNHHLINDF TVKQMRQGAF LVNTARGGLV DEKALAQALK EGRIRGAALD VHESEPFSFS QGPLKDAPNL ICTPHAAWYS EQASIEMREE AAREIRRAIT GRIPDSLKNC VNKDHLTAAT HWASMDPAVV HPELNGAAYR YPPGVVGVAP TGIPAAVEGI VPSAMSLSHG LPPVAHPPHA PSPGQTVKPE ADRDHASDQL.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CTBP1

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