CST3, His

Alternative Names: Cystatin-C, Cystatin-3, Neuroendocrine basic polypeptide, Gamma-trace, Post-gamma-globulin, CST3, MGC117328.

Cystatins are widespread proteinase inhibitors found in plants and animals. They form strong bonds with cysteine proteases like cathepsin B, H, L, and S. Cystatin C, a secreted molecule in this family, is of interest for biochemical, medical, and evolutionary studies. Cystatin C is a small protein with a molecular weight of 13260 Da, consisting of 120 amino acids without carbohydrates. It has two disulfide bridges near its carboxyl terminus. Elevated levels of cystatin C are associated with malignant diseases and renal insufficiency, making it a more effective marker than creatinine. Conversely, low levels of cystatin C contribute to the breakdown of elastic laminae and the development of atherosclerosis and abdominal aortic aneurysm.

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  • Sku: PSB-pro-656-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Cystatin C, His Tag is a protein that belongs to the cystatin family. This protein is widely used in various research applications due to its ability to inhibit cysteine proteases. With a molecular weight of approximately 14 kDa, Recombinant Human Cystatin C, His Tag offers a reliable and efficient tool for studying the regulation and function of cysteine proteases in biological systems. Its high purity and stability make it a valuable asset for scientists seeking to investigate protease-related processes.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation Filtered (0.4µm) and lyophilized from 0.5mg/ml in 20mM Tris buffer and 50mM NaCl pH-7.5.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Store lyophilized protein at –20°C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at –80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. Store lyophilized protein at –20°C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at –80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

Sample Prep Instruction

Add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

References

Not Available

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CST3, His

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