CSNK2B

Alternative Names: G5A, CSK2B, CSNK2B, CSNK 2B, CK2N, CK II beta, CK2B, Casein Kinase 2 beta, Casein Kinase 2 beta, Casein Kinase 2B, Casein kinase 2 beta polypeptide, Casein kinase II subunit beta, PKCK2 Beta, PKCK2B, MGC138222, MGC138224, Phosvitin

Casein Kinase 2 beta (CSNK2B) is a widely distributed Ser/Thr kinase found in all eukaryotes. It consists of two catalytic kinase domains, alpha subunits, and two identical regulatory beta subunits. CSNK2B plays a role in controlling the cell cycle, repairing DNA, regulating the circadian rhythm, and other cellular processes. The beta subunit, while not possessing kinase activity, contributes to the stability of the CK2 alpha subunit and is involved in determining activity and substrate specificity.

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  • Sku: PSB-pka-129-2µg
  • Vendor: ProSpec-Tany
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human Casein Kinase 2 beta is a protein that belongs to the casein kinase 2 (CK2) family. With a weight of approximately X kDa, it plays a significant role in various cellular processes. CK2 beta is involved in the regulation of cell growth, proliferation, and differentiation, making it a crucial component in maintaining cellular homeostasis. By modulating the activity of CK2 alpha, CK2 beta contributes to the phosphorylation of numerous target proteins, thereby influencing their functions. This recombinant protein serves as a valuable tool for studying the intricate mechanisms underlying CK2-mediated signaling pathways.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95.0 by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation CSNK2B protein solution (1mg/ml) in 0.2M NaCl, 20mM Tris-HCl buffer (pH 8.0), 1mM EDTA, 1mM DTT and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MSSSEEVSWI SWFCGLRGNE FFCEVDEDYI QDKFNLTGLN EQVPHYRQAL DMILDLEPDE ELEDNPNQSD LIEQAAEMLY GLIHARYILT NRGIAQMLEK YQQGDFGYCP RVYCENQPML PIGLSDIPGE AMVKLYCPKC MDVYTPKSSR HHHTDGAYFG TGFPHMLFMV HPEYRPKRPA NQFVPRLYGF KIHPMAYQLQ LQAASNFKSP VKTIR

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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CSNK2B
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