CSNK2A1

Alternative Names: EC 2.7.11.1, Casein kinase II subunit alpha, CK II, CK2A1, CKII alpha, CSNK2A1, PKCK2, CSK21.

Casein kinase 2 (CK2) is a serine/threonine-selective protein kinase that consists of two alpha subunits and two beta subunits. The alpha subunits contain the catalytic kinase domain. CK2 is involved in cell cycle control, DNA repair, regulation of the circadian rhythm, and other cellular processes. Activation of the Wnt signaling pathway leads to the activation of CK2. It has been observed that a Pertussis toxin-sensitive G protein and Disheveled act as intermediaries between Wnt-mediated activation of the Frizzled receptor and CK2 activation. Mice lacking CK2 alpha prime display abnormalities in the shape of developing sperm.

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  • Sku: PSB-pka-208-3µg
  • Vendor: ProSpec-Tany
$400.00 USD
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Title

Product Details

Product Description

Recombinant Human Casein Kinase 2 alpha 1 is a protein enzyme that belongs to the casein kinase 2 family. With a molecular weight of approximately 42 kDa, it plays a significant role in various cellular processes. This enzyme is involved in the phosphorylation of target proteins, regulating their functions and signaling pathways. Recombinant Human Casein Kinase 2 alpha 1 is widely studied due to its involvement in numerous biological processes, making it a valuable tool for scientific research and drug development.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 99.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CSNK2A1 is supplied in 25mM Tris-HCl, 500mM NaCl, 1mM DTT, 500μm PMSF, 50% glycerol, pH 8.5.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

Check Uniprot Link

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CSNK2A1

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