CRP

Alternative Names: PTX1, CRP, C-reactive protein, MGC88244, MGC149895.

CRP, an acute phase protein, is produced by hepatocytes during the acute phase response, in response to certain cytokines (IL-1 and TNF Alpha and Beta). Its levels increase significantly (up to 1,000 times) and it is a valuable indicator of inflammation in conditions including bacterial infection, rheumatoid arthritis, viral infections, transplantation rejection, meningitis, myocardial infarction, septicemia, osteomyelitis, and others. CRP is strongly associated with Serum Amyloid A levels.

  •
  • Sku: PSB-pro-335-0.5mg
  • Vendor: ProSpec-Tany
$240.00 USD
Shipping calculated at checkout.

Contact us directly for international purchases.

Title
Report Product Listing Issue (e.g. Missing Data, or Questions)
Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human C-Reactive Protein (rhCRP) is a protein derived through recombinant DNA technology, serving as a vital biomarker for inflammation and cardiovascular diseases. Belonging to the pentraxin family, rhCRP is a highly conserved acute-phase reactant primarily synthesized by hepatocytes in response to interleukin-6 stimulation. With a molecular weight of approximately 25 kDa, rhCRP plays a significant role in the innate immune system, facilitating the recognition and clearance of damaged cells and pathogens. Its measurement and analysis contribute to the understanding of various inflammatory conditions and aid in the assessment of disease progression and response to therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 95.0 % by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Dimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The sterile protein solution contains 20mM Tris (pH 7.5), 2mM CaCl2, 0.14M NaCl and 0.05% NaN3.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

Check Uniprot Link

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
View full details

CRP
SUBHEADING

Recently viewed products