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CRP (19-224 a.a.)

Alternative Names: MGC88244, MGC149895, PTX1, C-reactive protein, CRP.

CRP is a protein that is produced by liver cells, or hepatocytes, in response to certain cytokines (specifically IL-1, TNF Alpha and Beta) during the acute phase of an inflammatory response. The levels of CRP increase significantly (up to 1,000 times) and can be used as an indicator of inflammation in various conditions including bacterial infection, rheumatoid arthritis, viral infections, transplant rejection, meningitis, heart attack, septicemia, and osteomyelitis. Additionally, CRP levels are closely related to Serum Amyloid A levels.

  •
  • Sku: PSB-pro-914-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
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Product Details

Product Description

Recombinant Human C-Reactive Protein (19-224 a.a.) is a protein that belongs to the pentraxin family. With a molecular weight of approximately 25 kDa, it plays a significant role in the body's immune response. This protein is involved in the recognition and clearance of damaged cells and foreign pathogens, serving as a marker for inflammation. Recombinant Human C-Reactive Protein (19-224 a.a.) is widely studied due to its potential diagnostic and therapeutic applications in various inflammatory disorders.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 23.2 kDa
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation CRP protein solution (1mg/ml) containing 20mM Tris-HCl, pH8.0, 2M Urea and 20% Glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MQTDMSRKAF VFPKESDTSY VSLKAPLTKP LKAFTVCLHF YTELSSTRGY SIFSYATKRQ DNEILIFWSK DIGYSFTVGG SEILFEVPEV TVAPVHICTS WESASGIVEF WVDGKPRVRK SLKKGYTVGA EASIILGQEQ DSFGGNFEGS QSLVGDIGNV NMWDFVLSPD EINTIYLGGP FSPNVLNWRA LKYEVQGEVF TKPQLWP.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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CRP (19-224 a.a.)
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