CREG1

Alternative Names: Protein CREG1, Cellular repressor of E1A-stimulated genes 1, CREG.

CREG1 plays a dual role in gene expression, acting as both an activator and inhibitor to promote cellular proliferation and impede differentiation. It counteracts the transcriptional activation and cellular transformation induced by E1A. CREG1 exhibits certain sequence similarity with E1A and can bind to both the general transcription factor TBP and the tumor suppressor pRb in laboratory settings. Its involvement in the transcriptional regulation of cell growth and differentiation is notable.

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  • Sku: PSB-pro-1196-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Cellular Repressor of E1A-Stimulated Genes 1 (CREG1) is a protein that belongs to the CREG family. With a molecular weight of approximately X kDa, CREG1 plays a significant role in cellular processes by repressing the expression of genes stimulated by the E1A protein. This repressor protein is involved in regulating various cellular functions, making it a subject of interest in scientific research. Understanding the molecular properties and functions of CREG1 contributes to the comprehension of gene regulation mechanisms.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The CREG1 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMRGGRDH GDWDEASRLP PLPPREDAAR VARFVTHVSD WGALATISTL EAVRGRPFAD VLSLSDGPPG AGSGVPYFYL SPLQLSVSNL QENPYATLTM TLAQTNFCKK HGFDPQSPLC VHIMLSGTVT KVNETEMDIA KHSLFIRHPE MKTWPSSHNW FFAKLNITNI WVLDYFGGPK IVTPEEYYNV TVQ

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CREG1

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