CPSF4

Alternative Names: NAR, NEB1, Neb-1, CPSF30, CPSF 30 kDa subunit, NS1 effector domain-binding protein 1.

Cleavage And Polyadenylation Specific Factor 4 (CPSF4) is a crucial part of the CPSF4/YTH1 family, involved in pre-mRNA 3'-end formation. It recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase and other factors to induce cleavage and poly(A) addition. Specifically, CPSF4 has a preference for binding RNA polymers containing poly(U).

Skip to product information
  • Sku: PSB-pro-1406-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
 per 
Shipping calculated at checkout.

Contact us directly for international purchases.

Title

Product Details

Product Description

Recombinant Human Cleavage And Polyadenylation Specific Factor 4 (CPSF4) is a protein involved in the regulation of mRNA processing and polyadenylation. Belonging to the CPSF family, CPSF4 plays a significant role in the cleavage and polyadenylation of pre-mRNA molecules, thereby influencing gene expression. With a molecular weight of approximately X kDa, CPSF4 functions as a key component of the mRNA 3' end processing machinery. This protein's precise involvement in mRNA processing makes it a crucial player in gene expression regulation.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
29.9 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CPSF4 protein solution (1mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 0.4M UREA and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMQEIIAS VDHIKFDLEI AVEQQLGAQP LPFPGMDKSG AAVCEFFLKA ACGKGGMCPF RHISGEKTVV CKHWLRGLCK KGDQCEFLHE YDMTKMPECY FYSKFGECSN KECPFLHIDP ESKIKDCPWY DRGFCKHGPL CRHRHTRRVI CVNYLVGFCP EGPSCKFMHP RFELPMGTTE QPPLPQQTQP PAKQRTPQVI GVMQSQNSSA GNRGPRPLEQ VTCYKCGEKG HYANRCTKGH LAFLSGQ.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

View full details

CPSF4

SUBHEADING

Recently viewed products