CPEB1

Alternative Names: Cytoplasmic Polyadenylation Element-Binding Protein 1, CPE-Binding Protein 1, CPE-BP1, HCPEB-1, CPEB, Cytoplasmic Polyadenylation Element Binding Protein 1, CPEB-1, H-CEBP, CEBP, CPEB1.

CPEB1 is a member of the CPE binding protein family that regulates the translation of cyclin B1 during embryonic cell divisions. It is a conserved protein that binds to a specific RNA sequence called CPE, found in the 3' UTR of certain mRNAs. Similar proteins in Xenopus and mouse promote the cytoplasmic polyadenylation of inactive mRNAs with short polyA tails, leading to their translation.

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  • Sku: PSB-pro-1952-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1) is a member of the CPEB family, which plays a significant role in post-transcriptional regulation of gene expression. CPEB1 is a protein weighing approximately X kilodaltons (kDa) and is involved in the cytoplasmic polyadenylation process, which controls mRNA translation and stability. This protein binds to specific RNA sequences known as cytoplasmic polyadenylation elements (CPEs), thereby modulating the polyadenylation and subsequent translation of target mRNAs. By regulating gene expression at the post-transcriptional level, CPEB1 contributes to various cellular processes and is of particular interest in the field of molecular biology and genetics.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The CPEB1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAFPLEE EAGRIKDCWD NQEAPALSTC SNANIFRRIN AILDNSLDFS RVCTTPINRG IHDHLPDFQD SEETVTSRML FPTSAQESSR GLPDANDLCL GLQSLSLTGW DRPWSTQDSD SSAQSSTHSV LSMLHNPLGN VLGKPPLSFL PLDPLGSDLV DKFPAPSVRG SRLDTRPILD SRSSSPSDSD TSGFSSGSDH LSDLISSLRI SPPLPFLSLS GGGPRDPLKM GVGSRMDQEQ AALAAVTPSP TSASKRWPGA SVWPSWDLLE APKDPFSIER EARLHRQAAA VNEATCTWSG QLPPRNYKNP IYSCKVFLGG VPWDITEAGL VNTFRVFGSL SVEWPGKDGK HPRCPPKGYV YLVFELEKSV RSLLQACSHD PLSPDGLSEY YFKMSSRRMR CKEVQVIPWV LADSNFVRSP SQRLDPSRTV FVGALHGMLN AEALAAILND LFGGVVYAGI DTDKHKYPIG SGRVTFNNQR SYLKAVSAAF VEIKTTKFTK KVQIDPYLED SLCHICSSQP GPFFCRDQVC FKYFCRSCWH WRHSMEGLRH HSPLMRNQKN RDSS.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CPEB1

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