COPE

Alternative Names: Not Available

Recombinant Human Coatomer Protein Complex Subunit Epsilon, also known as COPE, is a protein involved in intracellular vesicle trafficking. Belonging to the coatomer family, COPE plays a critical role in maintaining cellular homeostasis by mediating the retrograde transport of proteins between the Golgi apparatus and the endoplasmic reticulum. With a molecular weight of approximately 33 kilodaltons, COPE acts as a subunit of the coatomer complex, which is responsible for the formation of coat proteins that facilitate vesicle budding and fusion. This recombinant protein is widely utilized in research studies to investigate the mechanisms underlying intracellular transport processes.

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  • Sku: PSB-pro-2120-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Coatomer Protein Complex Subunit Epsilon, also known as COPE, is a protein involved in intracellular vesicle trafficking. Belonging to the coatomer family, COPE plays a critical role in maintaining cellular homeostasis by mediating the retrograde transport of proteins between the Golgi apparatus and the endoplasmic reticulum. With a molecular weight of approximately 33 kilodaltons, COPE acts as a subunit of the coatomer complex, which is responsible for the formation of coat proteins that facilitate vesicle budding and fusion. This recombinant protein is widely utilized in research studies to investigate the mechanisms underlying intracellular transport processes.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
36.9 kDa
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation COPE protein solution (0.25 mg/ml) containing Phosphate buffered saline (pH7.4), 20% glycerol and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMAPPAPG PASGGSGEVD ELFDVKNAFY IGSYQQCINE AQRVKLSSPE RDVERDVFLY RAYLAQRKFG VVLDEIKPSS APELQAVRMF ADYLAHESRR DSIVAELDRE MSRSVDVTNT TFLLMAASIY LHDQNPDAAL RALHQGDSLE CTAMTVQILL KLDRLDLARK ELKRMQDLDE DATLTQLATA WVSLATGGEK LQDAYYIFQE MADKCSPTLL LLNGQAACHM AQGRWEAAEG LLQEALDKDS GYPETLVNLI VLSQHLGKPP EVTNRYLSQL KDAHRSHPFI KEYQAKENDF DRLVLQYAPS A.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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COPE

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