COA4

Alternative Names: Coiled-coil-helix-coiled-coil-helix domain-containing protein 8, CHCHD8, CMC3, Cytochrome c oxidase assembly factor 4 homolog, mitochondrial, E2-induced gene 2 protein, E2IG2, COA4.

COA4 is a crucial enzyme involved in the assembly of cytochrome c oxidase, the final enzyme in the mitochondrial respiratory chain. It relies on several accessory factors for its function. In addition to its role in oxidative phosphorylation, COA4 is also a component of macromolecular supercomplexes. The COX4 gene encodes a protein that, when defective, leads to acute human encephalomyopathies.

Skip to product information
  • Sku: PSB-pro-1988-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
 per 
Shipping calculated at checkout.

Contact us directly for international purchases.

Title

Product Details

Product Description

Recombinant Human Cytochrome C Oxidase Assembly Factor 4 is a protein involved in the assembly of cytochrome c oxidase, a key enzyme in the mitochondrial respiratory chain. Belonging to the cytochrome c oxidase assembly factor family, this protein plays a vital role in the proper functioning of the respiratory chain and oxidative phosphorylation. With a molecular weight of approximately X kDa, Recombinant Human Cytochrome C Oxidase Assembly Factor 4 is a crucial component in maintaining mitochondrial energy production and cellular respiration.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
12.5 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation COA4 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMSTSVPQ GHTWTQRVKK DDEEEDPLDQ LISRSGCAAS HFAVQECMAQ HQDWRQCQPQ VQAFKDCMSE QQARRQEELQ RRQEQAGAHH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

View full details

COA4

SUBHEADING

Recently viewed products