CNOT8

Alternative Names: CCR4-NOT transcription complex subunit 8, CCR4-associated factor 8, CAF1, CALIF, hCAF1, POP2, CAF1-like protein, CAF2, Caf1b, CNOT8.

CNOT8 is a subunit of the CCR4-NOT transcription complex. It belongs to the CAF1 family and plays a vital role in various processes. Along with other subunits, CNOT8 forms the CCR4-NOT complex, which acts as a general transcription regulation complex. This complex binds BTG2 and includes CHAF1A, CHAF1B, CNOT1, CNOT2, CNOT3, CNOT4, CNOT6, and CNOT8.

  •
  • Sku: PSB-pro-1517-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
Shipping calculated at checkout.

Contact us directly for international purchases.

Title
Report Product Listing Issue (e.g. Missing Data, or Questions)
Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human CCR4-NOT Transcription Complex, Subunit 8 is a protein that belongs to the CCR4-NOT transcription complex family. With a molecular weight of [insert weight], it plays a significant role in regulating gene expression and mRNA degradation. This subunit is involved in the formation of the CCR4-NOT complex, which is crucial for mRNA metabolism and transcriptional regulation in eukaryotes. Understanding the functions and interactions of Recombinant Human CCR4-NOT Transcription Complex, Subunit 8 is essential for unraveling the intricate mechanisms underlying gene regulation and cellular processes.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System E. coli
Purity 85.0 % by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 N/A
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation The CNOT8 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMPAALVE NSQVICEVWA SNLEEEMRKI REIVLSYSYI AMDTEFPGVV VRPIGEFRSS IDYQYQLLRC NVDLLKIIQL GLTFTNEKGE YPSGINTWQF NFKFNLTEDM YSQDSIDLLA NSGLQFQKHE EEGIDTLHFA ELLMTSGVVL CDNVKWLSFH SGYDFGYMVK LLTDSRLPEE EHEFFHILNL FFPSIYDVKY LMKSCKNLKG GLQEVADQLD LQRIGRQHQA GSDSLLTGMA FFRMKELFFE DSIDDAKYCG RLYGLGTGVA QKQNEDVDSA QEKMSILAII NNMQQ.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
View full details

CNOT8
SUBHEADING

Recently viewed products