CLTA

Alternative Names: CLTA, Clathrin light chain A, Lca

Clathrin, light chain A (CLTA) is a member of the clathrin protein family that functions as a regulatory element. It is a key coat protein in pits and vesicles that come from the plasma membrane and the trans-Golgi network. CLTA is involved in receptor-mediated endocytosis, where it encapsulates receptor proteins within Clathrin-coated vesicles.

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  • Sku: PSB-pro-1144-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Clathrin, Light Chain A is a protein that plays a significant role in the process of clathrin-mediated endocytosis, which is responsible for the internalization of various molecules into cells. Belonging to the clathrin family, this protein is involved in the assembly of clathrin coats on the cytoplasmic side of cellular membranes. With a molecular weight of approximately X kDa, Recombinant Human Clathrin, Light Chain A serves as a crucial component in the formation of clathrin-coated vesicles, facilitating the transport of cargo molecules within cells.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
26.2 kDa
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CLTA protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMAELDP FGAPAGAPGG PALGNGVAGA GEEDPAAAFL AQQESEIAGI ENDEAFAILD GGAPGPQPHG EPPGGPDAVD GVMNGEYYQE SNGPTDSYAA ISQVDRLQSE PESIRKWREE QMERLEALDA NSRKQEAEWK EKAIKELEEW YARQDEQLQK TKANNRAAEE AFVNDIDESS PGTEWERVAR LCDFNPKSSK QAKDVSRMRS VLISLKQAPL VH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CLTA

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