CLEC5A, Sf9

Alternative Names: Not Available

CLEC5A is a member of the CTL/CTLD superfamily and plays multiple roles including cell-cell signaling, cell adhesion, glycoprotein turnover, inflammation, and immune response. It serves as a cell attachment receptor for all 4 serotypes of Dengue virus and Japanese encephalitis virus. When CLEC5A binds to the dengue virus, it triggers signaling through the phosphorylation of TYROBP. This prevents viral entrance but stimulates the release of proinflammatory cytokines. CLEC5A also functions as a positive regulator of osteoclastogenesis and serves as a main regulator of synovial injury and bone erosion during autoimmune joint inflammation.

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  • Sku: PSB-pro-2554-1µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human C-Type Lectin Domain Family 5, Member A, Sf9 is a protein belonging to the C-Type Lectin Domain Family 5. This family is involved in various biological processes, including immune response and cell adhesion. With a molecular weight of approximately [insert weight], this protein plays a significant role in mediating interactions between cells and their environment. Its expression and function have been extensively studied in scientific research, contributing to a deeper understanding of cellular mechanisms.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Sf9 - Baculovirus cells
Purity 90.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
19.5 kDa
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CLEC5A protein solution (0.25mg/ml) contains 20% glycerol, 1mM DTT & Phosphate buffered saline (pH7.4).

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ADLPQIFNKS NDGFTTTRSY GTVSQIFGSS SPSPNGFITT RSYGTVCPKD WEFYQARCFF LSTSESSWNE SRDFCKGKGS TLAIVNTPEK LKFLQDITDA EKYFIGLIYH REEKRWRWIN NSVFNGNVTN QNQNFNCATI GLTKTFDAAS CDISYRRICE KNAKHHHHHH

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CLEC5A, Sf9

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