CLEC5A

Alternative Names: Not Available

CLEC5A, a member of the CTL/CTLD superfamily, serves various functions including cell-cell signaling, cell adhesion, glycoprotein turnover, inflammation, and immune response. It acts as a cell attachment receptor for all serotypes of Dengue virus and Japanese encephalitis virus. By binding to the dengue virus, CLEC5A triggers signaling through the phosphylation of TYROBP, causing no viral entrance but stimulating proinflammatory cytokine release. Additionally, CLEC5A plays a role in regulating osteoclastogenesis and is a key regulator of synovial injury and bone erosion during autoimmune joint inflammation.

Skip to product information
  • Sku: PSB-pro-2165-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
 per 
Shipping calculated at checkout.

Contact us directly for international purchases.

Title

Product Details

Product Description

Recombinant Human C-Type Lectin Domain Family 5, Member A (CLEC5A) is a protein belonging to the C-Type Lectin Domain Family 5. With a molecular weight of approximately X kilodaltons, CLEC5A plays a significant role in immune responses and inflammatory processes. This protein is involved in the recognition and binding of various pathogens, thereby initiating immune signaling cascades. By providing crucial insights into the molecular mechanisms underlying immune system function, CLEC5A contributes to our understanding of host-pathogen interactions and the development of potential therapeutic interventions for infectious diseases.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 80.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
20.8 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CLEC5A protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer, (pH8.0) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSPQIFNKS NDGFTTTRSY GTVSQIFGSS SPSPNGFITT RSYGTVCPKD WEFYQARCFF LSTSESSWNE SRDFCKGKGS TLAIVNTPEK LKFLQDITDA EKYFIGLIYH REEKRWRWIN NSVFNGNVTN QNQNFNCATI GLTKTFDAAS CDISYRRICE KNAK.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

View full details

CLEC5A

SUBHEADING

Recently viewed products