CLEC2D

Alternative Names: C-type lectin domain family 2 member D, CLAX1, LLT11, OCIL, C-type lectin domain family 2 member D, CLAX1, LLT11, OCIL.

The C-type lectin domain family 2, or CLEC2D, serves as a receptor for KLRB1, protecting target cells from being destroyed by natural killer cells. Recent studies have demonstrated that CLEC2D is capable of inhibiting the formation of bone cells called osteoclasts and reducing bone resorption. This protein regulates the release of interferon-gamma and possesses a transmembrane domain close to the N-terminus, similar to the C-type lectin-like extracellular domain.

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  • Sku: PSB-pro-2650-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human C-type Lectin Domain Family 2, Member D (CLEC2D) is a protein belonging to the C-type lectin domain family. With a molecular weight of approximately [insert weight], CLEC2D plays a significant role in immune response modulation and cell adhesion processes. This protein exhibits binding affinity towards various glycosylated ligands, thereby participating in diverse physiological and pathological events. Understanding the intricate mechanisms and functions of CLEC2D provides valuable insights into its potential therapeutic applications in immunotherapy and disease management.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The CLEC2D solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M urea.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSRANCHQE PSVCLQAACP ESWIGFQRKC FYFSDDTKNW TSSQRFCDSQ DADLAQVESF QELNFLLRYK GPSDHWIGLS REQGQPWKWI NGTEWTRQFP ILGAGECAYL NDKGASSARH YTERKWICSK SDIHV

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CLEC2D

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