CKS2

Alternative Names: CDC28, CDC28 Protein Kinase 2, CKS2, CKSHS2

The CKS2 protein interacts with cyclin dependent kinases to regulate cell cycle progression. It plays a crucial role in the first metaphase/anaphase transition during meiosis and is essential for early embryogenesis and cell cycle progression in somatic cells. Increased expression of CKS2 has been found to protect cells from apoptosis. The CKS2 mRNA exhibits varying expression patterns throughout the cell cycle in HeLa cells, highlighting the specific role of the encoded protein.

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  • Sku: PSB-pka-258-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human CDC28 protein kinase 2 is a member of the cyclin-dependent protein kinase (CDK) family, which plays a critical role in regulating cell cycle progression. With a molecular weight of approximately 34 kDa, this protein kinase is involved in phosphorylating key cell cycle proteins to control the transition between different phases of the cell cycle. Recombinant Human CDC28 protein kinase 2 is commonly used in research settings to study cell cycle regulation and potential therapeutic targets for cancer treatment.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The CKS2 protein solution contains 20mM Tris-HCl pH-7.5 and 20% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MASMTGGQQM GRGSHMAHKQ IYYSDKYFDE HYEYRHVMLP RELSKQVPKT HLMSEEEWRRLGVQQSLGWV HYMIHEPEPH ILLFRRPLPK DQQ.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CKS2

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