CKMB Type-1

Alternative Names: CKMB, CKMBI, CKMBITI, Creatine Kinase MB Isoenzyme Type-I

The isoenzymes MM, MB, and BB, which are found in muscle, cardiac, and brain tissues, can be used for calibrating diagnostic instruments and studying neuromuscular diseases. Creatine Kinases have various applications in neuromuscular conditions including cardiac disease, mitochondrial disorders, inflammatory myopathies, myasthenia, polymyositis, McArdle's disease, NMJ disorders, muscular dystrophy, ALS, hypo and hyperthyroid disorders, central core disease, acid maltase deficiency, myoglobinuria, rhabdomyolysis, motor neuron diseases, rheumatic diseases, and others that affect the levels of Creatine Kinases.

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  • Sku: PSB-cki-269-10µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Creatine Kinase MB Isoenzyme Type-1 is a protein belonging to the creatine kinase family. This enzyme plays a vital role in the energy metabolism of various tissues, particularly in the heart and skeletal muscles. With a molecular weight of approximately 87 kDa, Recombinant Human Creatine Kinase MB Isoenzyme Type-1 catalyzes the reversible transfer of a phosphate group between creatine and adenosine diphosphate (ADP), thereby facilitating the generation of adenosine triphosphate (ATP) – the primary source of cellular energy. Its precise and controlled functioning is crucial for maintaining proper cellular energy homeostasis.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Pichia Pastoris
Purity 95% by SDS-PAGE
Activity
486 IU/mg at 37°C. 486 IU/mg at 37°C.
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Dimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The 7.9mg/ml proteinsolution contains 0.02M Potassium Phosphate, 1mM DTT and 50% glycerol, pH 5.0-6.0.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CKMB Type-1

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