CISD1

Alternative Names: CDGSH Iron Sulfur Domain 1, CDGSH Iron Sulfur Domain-Containing Protein 1, Chromosome 10 Open Reading Frame 70, Zinc Finger CDGSH-Type Domain 1, C10orf70, ZCD1, MitoNEET, MDS029.

CISD1 protein contains a CDGSH iron-sulfur domain and interacts with a redox-active [2Fe-2S] cluster. CISD1 is specifically localized in the outer membrane of mitochondria and plays a role in the regulation of oxidation.

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  • Sku: PSB-pro-1221-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human CDGSH Iron Sulfur Domain 1 (CISD1) is a protein that belongs to the CDGSH iron sulfur domain family. With a molecular weight of approximately X kilodaltons, CISD1 is involved in various cellular processes related to iron metabolism and oxidative stress response. This protein plays a role in maintaining mitochondrial function and has been implicated in the pathogenesis of several diseases, including neurodegenerative disorders. Understanding the structural and functional characteristics of CISD1 can provide valuable insights into its physiological roles and potential therapeutic targets.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The CISD1 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSKRFYVKD HRNKAMINLH IQKDNPKIVH AFDMEDLGDK AVYCRCWRSK KFPFCDGAHT KHNEETGDNV GPLIIKKKET

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CISD1

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