CHRNA6

Alternative Names: CHNRA6, CHRNA6, Neuronal acetylcholine receptor subunit alpha-6

CHRNA6 is a member of the nicotinic acetylcholine receptors (nAChRs) family. nAChRs are ion channels formed by the combination of alpha and beta protein subunits. Upon binding acetylcholine, the receptors undergo a conformational change, which opens ion-conducting channels in the cell membrane. CHRNA6 receptors are mainly found in the nigrostriatal pathway.

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  • Sku: PSB-pro-1878-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Cholinergic Receptor Nicotinic Alpha 6 is a protein that belongs to the family of cholinergic receptors, specifically the nicotinic receptor subfamily. With a weight of approximately X kilodaltons, this protein plays a significant role in mediating the effects of acetylcholine, a neurotransmitter, on the central and peripheral nervous systems. It is involved in various physiological processes, including synaptic transmission, muscle contraction, and cognitive functions. Understanding the structure and function of Recombinant Human Cholinergic Receptor Nicotinic Alpha 6 can provide valuable insights into the development of therapeutic strategies targeting cholinergic signaling pathways.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85.0% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
29.3 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CHRNA6 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSKGCV GCATEERLFH KLFSHYNQFI RPVENVSDPV TVHFEVAITQ LANVDEVNQI METNLWLRHI WNDYKLRWDP MEYDGIETLR VPADKIWKPD IVLYNNAVGD FQVEGKTKAL LKYNGMITWT PPAIFKSSCP MDITFFPFDH QNCSLKFGSW TYDKAEIDLL IIGSKVDMND FWENSEWEII DASGYKHDIK YNCCEEIYTD ITYSFYIRRL.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CHRNA6

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