CHRAC1

Alternative Names: CHARC1, CHRAC-1, CHRAC15, CHRAC-15, YCL1, Chromatin accessibility complex protein 1, Chromatin accessibility complex 15 kDa protein, DNA polymerase epsilon subunit p15.

CHRAC1 is a histone-fold protein that binds DNA without having a specific sequence. It interacts with other histone-fold proteins and combines with them to form bigger enzymatic complexes for processes like DNA replication, transcription, and packaging.

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  • Sku: PSB-pro-1391-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Chromatin Accessibility Complex 1 (CHRAC1) is a protein complex that plays a significant role in regulating chromatin structure and accessibility. Belonging to the ATP-dependent chromatin remodeling family, CHRAC1 is involved in the dynamic modification of DNA packaging, thereby influencing gene expression. With a molecular weight of approximately X kDa, CHRAC1 functions by utilizing ATP hydrolysis to alter the interaction between DNA and histone proteins, ultimately impacting the accessibility of transcription factors to specific genomic regions. This recombinant complex has been extensively studied for its involvement in various cellular processes, making it a valuable tool for investigating chromatin remodeling mechanisms and their implications in gene regulation.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Heterodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CHRAC1 protein solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMADVVVG KDKGGEQRLI SLPLSRIRVI MKSSPEVSSI NQEALVLTAK ATELFVQCLA TYSYRHGSGK EKKVLTYSDL ANTAQQSETF QFLADILPKK ILASKYLKML KEEKREEDEE NDNDNESDHD EADS.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CHRAC1

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