CFL1

Alternative Names: CFL-1, CFL1, Cofilin-1, Cofilin1, Cofilin, non-muscle isoform, 18 kDa phosphoprotein, p18.

Cofilin is a group of actin-binding proteins that dismantle actin filaments. This intracellular protein is present in many organisms and can bind and break down filamentous F-actin, as well as prevent the formation of monomeric G-actin into polymers. Cofilin is also implicated in the movement of the actin-cofilin complex from the cytoplasm to the nucleus.

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  • Sku: PSB-pro-591-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Cofilin-1 is a protein that plays a vital role in regulating actin dynamics, which is crucial for cellular processes such as cell motility, cytokinesis, and intracellular trafficking. Belonging to the actin-binding protein family, this protein weighs approximately 19 kilodaltons (kDa). With its ability to depolymerize actin filaments, Recombinant Human Cofilin-1 contributes to the reorganization of the actin cytoskeleton, thereby influencing various cellular functions. This recombinant protein is widely studied in scientific research for its involvement in cell migration, development, and disease progression.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 95.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The protein solution contains 20mM Tris pH-8 and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MASGVAVSDG VIKVFNDMKV RKSSTPEEVK KRKKAVLFCLSEDKKNIILE EGKEILVGDV GQTVDDPYAT FVKMLPDKDC RYALYDATYE TKESKKEDLVFIFWAPESAP LKSKMIYASS KDAIKKKLTG IKHELQANCY EEVKDRCTLA EKLGGSAVIS LEGKPL.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CFL1

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