CEACAM8

Alternative Names: Carcinoembryonic antigen-related cell adhesion molecule 8, Carcinoembryonic antigen CGM6, Non-specific cross-reacting antigen NCA-95, CD66b, CD67 antigen, CGM6, CD67, NCA-95, CEACAM8

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8) is a glycoprotein on the surface of cells. It plays a role in cell adhesion, particularly with other similar molecules like CEACAM6. CEACAM8 is involved in cell migration, adhesion, and binding to pathogens. It is mainly found on the surface of eosinophils in human peripheral blood and is used as a marker for granulocytes.

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  • Sku: PSB-pro-2716-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 (CEACAM8) is a glycosylphosphatidylinositol-anchored protein that belongs to the carcinoembryonic antigen (CEA) family. With a molecular weight of approximately 80 kDa, CEACAM8 is predominantly expressed on the surface of neutrophils and plays a significant role in various immune responses. This protein mediates cell-cell adhesion and regulates neutrophil migration and activation. CEACAM8's involvement in immune surveillance and its potential as a diagnostic marker in certain diseases make it a subject of scientific interest.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Sf9 - Baculovirus cells
Purity 95.0 by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
32.3 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The CEACAM8 solution (1mg/1ml) contains Phosphate-Buffered Saline (pH 7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

QLTIEAVPSN AAEGKEVLLL VHNLPQDPRG YNWYKGETVD ANRRIIGYVI SNQQITPGPA YSNRETIYPN ASLLMRNVTR NDTGSYTLQV IKLNLMSEEV TGQFSVHPET PKPSISSNNS NPVEDKDAVA FTCEPETQNT TYLWWVNGQS LPVSPRLQLS NGNRTLTLLS VTRNDVGPYE CEIQNPASAN FSDPVTLNVL YGPDAPTISP SDTYYHAGVN LNLSCHAASN PPSQYSWSVN GTFQQYTQKL FIPNITTKNS GSYACHTTNS ATGRNRTTVR MITVSDHHHH HH

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CEACAM8

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