CEACAM3, Sf9

Alternative Names: CEA, CEACAM3, Carcinoembryonic Antigen CGM1, Carcinoembryonic Antigen Gene Family Member 1, Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3, CD66d Antigen, CD66D, CGM1, Nonspecific Cross-Reacting Antigen, W264, W282

CEACAM3, a member of the immunoglobulin superfamily, is an important cell adhesion protein found in higher concentrations in tumor tissues compared to normal tissues. It plays a crucial role in clearing pathogens through the innate immune system and also promotes RAC1 stimulation during pathogen phagocytosis.

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  • Sku: PSB-pro-2443-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3) is a glycosylphosphatidylinositol-anchored protein belonging to the carcinoembryonic antigen (CEA) family. With a molecular weight of approximately 70 kDa, CEACAM3 is primarily expressed on neutrophils and plays a significant role in various immune responses. Its involvement in cell adhesion, phagocytosis, and bacterial recognition highlights its importance in innate immunity. Understanding the functional properties of CEACAM3 contributes to the comprehension of neutrophil-mediated immune processes and the development of potential therapeutic strategies.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Sf9 - Baculovirus cells
Purity 95.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
14.2 kDa
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CEACAM3 protein solution (1mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ADPKLTIESM PLSVAEGKEV LLLVHNLPQH LFGYSWYKGE RVDGNSLIVG YVIGTQQATP GAAYSGRETI YTNASLLIQN VTQNDIGFYT LQVIKSDLVN EEATGQFHVY QENAPGLPVG AVAGHHHHHH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CEACAM3, Sf9

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