CEACAM1

Alternative Names: Not Available

CEACAM1 is a cell adhesion protein that belongs to the CEA gene family, a subset of the immunoglobulin superfamily. It facilitates homophilic cell adhesion independently of calcium. CEACAM1 is found on the surface of multiple cell types, including blood, epithelial, and vascular cells. In addition to its adhesive function, CEACAM1 acts as a coinhibitory receptor in immune responses and contributes to angiogenesis.

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  • Sku: PSB-pro-2352-2µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) is a glycoprotein that belongs to the carcinoembryonic antigen-related cell adhesion molecule family. With a weight of approximately 100-115 kDa, CEACAM1 plays a significant role in cell adhesion, signal transduction, and immune response modulation. This molecule is involved in various physiological processes, including embryogenesis, angiogenesis, and tumor suppression. Understanding the structural and functional aspects of CEACAM1 can provide valuable insights into its potential implications in cancer research and therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Sf9 - Baculovirus cells
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
44.6 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CEACAM1protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ADPEFQLTTE SMPFNVAEGK EVLLLVHNLP QQLFGYSWYK GERVDGNRQI VGYAIGTQQA TPGPANSGRE TIYPNASLLI QNVTQNDTGF YTLQVIKSDL VNEEATGQFH VYPELPKPSI SSNNSNPVED KDAVAFTCEP ETQDTTYLWW INNQSLPVSP RLQLSNGNRT LTLLSVTRND TGPYECEIQN PVSANRSDPV TLNVTYGPDT PTISPSDTYY RPGANLSLSC YAASNPPAQY SWLINGTFQQ STQELFIPNI TVNNSGSYTC HANNSVTGCN RTTVKTIIVT ELSPVVAKPQ IKASKTTVTG DKDSVNLTCS TNDTGISIRW FFKNQSLPSS ERMKLSQGNT TLSINPVKRE DAGTYWCEVF NPISKNQSDP IMLNVNYNAL PQENGLSPGH HHHHH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CEACAM1

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