CDO1

Alternative Names: Cysteine dioxygenase type I, Cysteine dioxygenase type 1, CDO-I, CDO, CDO1.

CDO1 is a mammalian enzyme that plays a crucial role in metabolic pathways related to pyruvate and sulfur-containing compounds. It converts L-cysteine into cysteine sulfinic acid by incorporating dioxygen. CDO1 helps regulate cellular cysteine levels and is particularly important for maintaining proper levels of free cysteine in the liver. It is highly expressed in the liver and placenta, but has low expression in the heart, brain, and pancreas. CDO1 can also be found in HepG2 cells.

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  • Sku: PSB-enz-449-10µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Cysteine Dioxygenase is an enzyme that belongs to the cysteine dioxygenase family. It plays a role in the metabolism of cysteine, converting it into cysteine sulfinic acid. This enzyme has a molecular weight of approximately 24 kDa. Recombinant Human Cysteine Dioxygenase is commonly used in research and biotechnology applications for its ability to catalyze the oxidation of cysteine.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
23.9 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The CDO1 solution contains 20mM Tris buffer(pH 8.0), 10% glycerol and 1mM DTT.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMEQ TEVLKPRTLA DLIRILHQLF AGDEVNVEEV QAIMEAYESD PTEWAMYAKF DQYRYTRNLV DQGNGKFNLM ILCWGEGHGS SIHDHTNSHC FLKMLQGNLK ETLFAWPDKK SNEMVKKSER VLRENQCAYI NDSVGLHRVE NISHTEPAVS LHLYSPPFDT CHAFDQR.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CDO1

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