CD93

Alternative Names: CD93 Molecule, CD93 Antigen, CDw93, DJ737E23.1, ECSM3, Complement Component 1, Q Subcomponent, Receptor 1, Complement Component 1 Q Subcomponent Receptor 1, C1q/MBL/SPA Receptor, C1qR(P), C1Qrp, C1QR1, C1qR, C1q Receptor 1, Matrix-Remodeling-Associated Protein 4, Matrix-Remodelling Associated 4, MXRA4

CD93 is a receptor component of a larger receptor complex that includes C1q, MBL2-mannose-binding lectin, and SPA-pulmonary surfactant protein A. It plays a role in enhancing phagocytosis in monocytes and macrophages when interacting with soluble defense collagens. CD93 is also involved in intercellular adhesion. Additionally, CD93 is expressed on plasmablasts and plasma cells, including long-lived plasma cells. These cells have reduced cell cycle activity, increased levels of isotype-switched Ig secretion, and an altered transcriptional network. CD93 is critical for the maintenance of plasma cells in bone marrow niches.

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  • Sku: PSB-pro-2336-1µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human CD93, a glycoprotein, is a member of the C-type lectin domain family 14A (CLEC14A). This protein plays a significant role in various biological processes, including angiogenesis, inflammation, and immune response. With a molecular weight of approximately 120 kDa, Recombinant Human CD93 is involved in cell adhesion and migration, as well as regulating endothelial cell proliferation. Its unique characteristics make it a valuable target for studying vascular biology and developing therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Sf9 - Baculovirus cells
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
59.3 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CD93 protein solution (0.5mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

TGADTEAVVC VGTACYTAHS GKLSAAEAQN HCNQNGGNLA TVKSKEEAQH VQRVLAQLLR REAALTARMS KFWIGLQREK GKCLDPSLPL KGFSWVGGGE DTPYSNWHKE LRNSCISKRC VSLLLDLSQP LLPSRLPKWS EGPCGSPGSP GSNIEGFVCK FSFKGMCRPL ALGGPGQVTY TTPFQTTSSS LEAVPFASAA NVACGEGDKD ETQSHYFLCK EKAPDVFDWG SSGPLCVSPK YGCNFNNGGC HQDCFEGGDG SFLCGCRPGF RLLDDLVTCA SRNPCSSSPC RGGATCVLGP HGKNYTCRCP QGYQLDSSQL DCVDVDECQD SPCAQECVNT PGGFRCECWV GYEPGGPGEG ACQDVDECAL GRSPCAQGCT NTDGSFHCSC EEGYVLAGED GTQCQDVDEC VGPGGPLCDS LCFNTQGSFH CGCLPGWVLA PNGVSCTMGP VSLGPPSGPP DEEDKGEKEG STVPRAATAS PTRGPEGTPK ATPTTSRPSL SSDAPITSAP LKMLAPSGSP GVWREPSIHH ATAASGPQEP AGGDSSVATQ NNDGTDGQKV EHHHHHH

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CD93

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