CD81

Alternative Names: CD81 Molecule, CD81 Antigen (Target Of Antiproliferative Antibody 1), 26 KDa Cell Surface Protein TAPA-1, Tetraspanin-28, CD81 Antigen, Tspan-28, TSPAN28, TAPA1, Target Of The Antiproliferative Antibody 1, CVID6, S5.7, 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1, Tetraspanin-28, Tspan-28.

CD81 antigen isoform 1, a component of the tetraspanin family, interacts with IGSF8 (CD316) and CD36. In B cells, CD81 forms a complex with CD21, CD19, and Leu13, reducing the threshold for B cell activation via the linkage of antigen-specific recognition and CD21 mediator recognition. CD81 also connects with CD4 and CD8 on T cells, providing a costimulatory signal with CD3.

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  • Sku: PSB-pro-2472-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Safety Data Sheet
UniProt Listing
NCBI Link

Product Details

Product Description

Recombinant Human CD81 is a protein that belongs to the tetraspanin family. With a molecular weight of approximately 26 kDa, it plays a significant role in various cellular processes. CD81 is involved in cell adhesion, migration, and signaling events, making it a crucial component in immune responses and viral infections. Its interaction with other proteins, such as integrins and receptors, enables CD81 to regulate diverse physiological functions. This recombinant protein is widely used in scientific research to investigate the mechanisms underlying cellular processes and to develop therapeutic interventions.

Current Lead Time

7-14 Days

Product Specifications

Species
 Human
Expression System Sf9 - Baculovirus cells
Purity 95.0 % by SDS-PAGE
Activity
 Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
 37.0 kDa
Structure Homodimer
Endotoxin Concentration
 Not Available
Purification Method Not Available
Form
 Frozen
Formulation CD81 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ADPFVNKDQI AKDVKQFYDQ ALQQAVVDDD ANNAKAVVKT FHETLDCCGS STLTALTTSV LKNNLCPSGS NIISNLFKED CHQKIDDLFS GKLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution
​

References

Not Available
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CD81
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