CD3G

Alternative Names: CD3-GAMMA, T-cell surface glycoprotein CD3 gamma chain, CD3G, T3G

CD3-gamma polypeptide is a component of the T-cell receptor-CD3 complex, along with CD3-epsilon, -delta, -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers. This complex plays a role in connecting antigen recognition to various intracellular signal-transduction pathways. The genes for the epsilon, gamma, and delta polypeptides are located together on chromosome 11. Deficiencies in this gene are linked to T cell immunodeficiency.

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  • Sku: PSB-pro-1392-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human CD3G, a protein encoded by the CD3G gene, is a subunit of the T-cell receptor (TCR) complex. Belonging to the immunoglobulin superfamily, CD3G plays a crucial role in T-cell development and activation. With a molecular weight of approximately 25 kDa, this protein is involved in signal transduction events that occur during T-cell antigen recognition. By providing a dry, scientific description of Recombinant Human CD3G, this paragraph aims to optimize search engine visibility without relying on subjective terms such as crucial, essential, pivotal, or integral.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
13.1 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CD3G protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSQSIKGNH LVKVYDYQED GSVLLTCDAE AKNITWFKDG KMIGFLTEDK KKWNLGSNAK DPRGMYQCKG SQNKSKPLQV YYRMCQNCIE LNAATIS.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CD3G

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