CD300E

Alternative Names: CD300E Molecule, CD300E Antigen, CD300LE, IREM2, CLM2, Immune Receptor Expressed On Myeloid Cells 2, Polymeric Immunoglobulin Receptor 2, CD300 Antigen Like Family Member E, CD300 Antigen-Like Family Member E, Poly-Ig Receptor 2, CMRF35-A5, PIgR2, CMRF35-Like Molecule 2, CMRF35A5

CD300E is a member of the CD300 family and is a precursor to the CMRF35-like molecule 2. It is a 205 amino acid single-pass type I membrane protein with one Ig-like V-type domain. It is believed that CD300E acts as an activating receptor when interacting with DAP12. CD300E is found on the surface of mature hematopoietic cells in the monocyte and myeloid lineages.

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  • Sku: PSB-pro-2114-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human CD300E is a protein belonging to the CD300 family, which comprises cell surface receptors involved in various immune responses. With a molecular weight of approximately X kDa, CD300E plays a significant role in modulating immune cell activities. This protein is of particular interest due to its potential implications in immune-related disorders and its involvement in regulating immune cell activation and cytokine production. Understanding the functional properties and mechanisms of CD300E may provide valuable insights into the development of targeted therapeutic interventions for immune-related diseases.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
19.9 kDa
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CD300E protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0).

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSLKGPGSV TGTAGDSLTV WCQYESMYKG YNKYWCRGQY DTSCESIVET KGEEKVERNG RVSIRDHPEA LAFTVTMQNL NEDDAGSYWC KIQTVWVLDS WSRDPSDLVR VYVSPAITTP RRTTHPATPP IFLVVNPGRN LSTGEVLTQN SGFRLSSPH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CD300E

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