CD2, Sf9

Alternative Names: CD2 antigen, CD2, T11, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, Erythrocyte receptor, Rosette receptor, SRBC.

CD2, also known as E-rosette receptor, T11, and lymphocyte function antigen-2 (LFA-2), is found on T cells, thymocytes, and a subset of natural killer cells. It acts as a receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). CD2 promotes the phosphorylation of proteins p56lck, p59fyn, CD3eta, and CD3epsilon when stimulated. Its functions include T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and the regulation of T cell anergy.

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  • Sku: PSB-pro-2390-2µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human CD2, Sf9 is a protein that belongs to the immunoglobulin superfamily. With a molecular weight of approximately X kDa, it plays a significant role in T-cell activation and adhesion processes. This protein is commonly used in research and biotechnological applications due to its ability to facilitate cell-cell interactions and modulate immune responses. Recombinant Human CD2, Sf9 is a valuable tool in studying various cellular processes and understanding the mechanisms underlying immune system function.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Sf9 - Baculovirus cells
Purity 95.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
22.3 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CD2 protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ADPKEITNAL ETWGALGQDI NLDIPSFQMS DDIDDIKWEK TSDKKKIAQF RKEKETFKEK DTYKLFKNGT LKIKHLKTDD QDIYKVSIYD TKGKNVLEKI FDLKIQERVS KPKISWTCIN TTLTCEVMNG TDPELNLYQD GKHLKLSQRV ITHKWTTSLS AKFKCTAGNK VSKESSVEPVSCPEKGLDHH HHHH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CD2, Sf9

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