CD2 GST

Alternative Names: CD2 antigen, CD2, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, T11, LFA-2, LFA-3 receptor, Erythrocyte receptor, Rosette receptor, SRBC.

CD2, or the E-rosette receptor/T11/Lymphocyte function antigen-2 (LFA-2), is found on T cells, thymocytes, and a subset of natural killer cells. It acts as a receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). After CD2 stimulation, tyrosine phosphorylation occurs in p56lck, p59fyn, CD3eta, and CD3epsilon. CD2 is involved in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.

Skip to product information
  • Sku: PSB-pro-468-2µg
  • Vendor: ProSpec-Tany
$175.00 USD
 per 
Shipping calculated at checkout.

Contact us directly for international purchases.

Title

Product Details

Product Description

Recombinant Human CD2, GST Tag is a fusion protein that belongs to the immunoglobulin superfamily. It is commonly used in research and diagnostic applications due to its ability to specifically bind to CD58, facilitating cell adhesion and activation. This protein has a molecular weight of approximately 45 kDa and is expressed in a prokaryotic system. The GST (glutathione S-transferase) tag allows for easy purification and detection of the protein. Its precise and controlled binding properties make it a valuable tool in various immunological studies.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CD2 at 100µg/ml in 50mM Tris-HCl pH7.5 and 10Mm L-glutathione (reduced).

*For Research Use Only

Notes

Applications: • ELISA • Inhibition Assays • Western Blotting

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

Check Uniprot Link

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

View full details

CD2 GST

SUBHEADING

Recently viewed products