CD160

Alternative Names: CD160 Molecule, CD160 Antigen, Natural Killer Cell Receptor BY55, BY55, Natural Killer Cell Receptor, Immunoglobulin Superfamily Member, CD160 Transmembrane Isoform, CD160-Delta Ig, NK28, NK1, CD160

CD160 is a receptor found on human natural killer (NK) cells and certain T-cell subsets. It plays a role in tumor-specific immune responses and has potential as a target for therapy and monitoring of minimal residual disease. CD160 also acts as a coinhibitory molecule on T-cells, interacting with a protein called herpesvirus entry mediator (HVEM) to deliver an inhibitory signal. It is highly expressed on NK cells, CD8 T lymphocytes with cytolytic activity, and all intestinal intraepithelial lymphocytes. CD160 has a wide binding specificity for both classical and nonclassical MHC class I molecules.

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  • Sku: PSB-pro-2419-1µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human CD160 is a protein that belongs to the immunoglobulin superfamily. It is a cell surface receptor expressed on natural killer (NK) cells, T cells, and some B cells. With a molecular weight of approximately 27 kDa, CD160 plays a role in regulating immune responses and is involved in the activation and cytotoxicity of NK cells. This recombinant protein is widely used in research studies to investigate its functions and potential therapeutic applications.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Sf9 - Baculovirus cells
Purity 90.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
15.9 kDa
Structure Monomer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation CD160 protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

ADLINITSSA SQEGTRLNLI CTVWHKKEEA EGFVVFLCKD RSGDCSPETS LKQLRLKRDP GIDGVGEISS QLMFTISQVT PLHSGTYQCC ARSQKSGIRL QGHFFSILFT ETGNYTVTGL KQRQHLEFSH NEGTLSHHHH HH.

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CD160

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