CAMLG

Alternative Names: CAML, Calcium-Modulating Cyclophilin Ligand, Calcium-Signal Modulating Cyclophilin Ligand, Calcium Modulating Ligand, Cyclophilin B-Binding Protein.

CAMLG is a membrane protein that plays a crucial role in calcium signal transduction pathway. It binds to cyclophilin B and acts as a mediator between the TCR and calcineurin. By facilitating the entry of calcium ions, it links cyclophilin B to calcium signaling.

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  • Sku: PSB-pro-1612-5µg
  • Vendor: ProSpec-Tany
$60.00 USD
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Title

Product Details

Product Description

Recombinant Human Calcium Modulating Ligand is a protein that plays a significant role in the regulation of calcium levels within the body. Belonging to the family of calcium-binding proteins, this ligand acts as a modulator, fine-tuning the intricate balance of calcium ions. With a molecular weight of approximately [insert weight], this ligand interacts with calcium channels and receptors, influencing their activity and ultimately impacting various cellular processes. Its precise functions and mechanisms are of great interest in scientific research, offering potential insights into the broader understanding of calcium homeostasis and associated pathologies.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 85 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
23.2 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The CAMLG solution contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 10% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSMESMAVA TDGGERPGVP AGSGLSASQR RAELRRRKLL MNSEQRINRI MGFHRPGSGA EEESQTKSKQ QDSDKLNSLS VPSVSKRVVL GDSVSTGTTD QQGGVAEVKG TQLGDKLDSF IKPPECSSDV NLELRQRNRG DLTADSVQRG SRHGLEQYLS RFEEAMKLRK QLISEKPSQE DGNTTEEFDS FR

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CAMLG

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