CALM

Alternative Names: CaM, CALM, Calmodulin

Human calmodulin is a calcium-binding protein that plays a significant role in regulating various cellular processes. Belonging to the EF-hand superfamily, it acts as an intracellular receptor for calcium ions, facilitating their signaling and mediating their effects on target proteins. With a molecular weight of approximately 17 kDa, calmodulin consists of two globular domains, each containing two calcium-binding EF-hand motifs. Its diverse functions encompass the regulation of enzyme activity, ion channel gating, neurotransmitter release, muscle contraction, and gene expression. Understanding the intricate mechanisms of human calmodulin is crucial for unraveling the complexities of calcium signaling in cellular physiology and disease progression.

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  • Sku: PSB-pro-2799-100µg
  • Vendor: ProSpec-Tany
$500.00 USD
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Title

Product Details

Product Description

Human calmodulin is a calcium-binding protein that plays a significant role in regulating various cellular processes. Belonging to the EF-hand superfamily, it acts as an intracellular receptor for calcium ions, facilitating their signaling and mediating their effects on target proteins. With a molecular weight of approximately 17 kDa, calmodulin consists of two globular domains, each containing two calcium-binding EF-hand motifs. Its diverse functions encompass the regulation of enzyme activity, ion channel gating, neurotransmitter release, muscle contraction, and gene expression. Understanding the intricate mechanisms of human calmodulin is crucial for unraveling the complexities of calcium signaling in cellular physiology and disease progression.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System Human brain
Purity 95.0 % by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) No
Molecular Weight
N/A
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Lyophilized
Formulation CALM was lyophilized with 2mM EDTA.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Storage Instruction

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

Sample Prep Instruction

It is recommended to reconstitute the lyophilized CALM in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

References

Not Available

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CALM

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