CA8

Alternative Names: Carbonic anhydrase VIII, CA-VIII, CA-related protein, carbonic anhydrase-like sequence, carbonic anhydrase-related protein, carbonate dehydratase, CALS, CARP, CAMRQ3.

CA8 was initially classified as a CA-related protein due to its sequence resemblance to other carbonic anhydrase genes, but it does not possess carbonic anhydrase activity. Despite this, it is still designated as a carbonic anhydrase based on its genetic similarity to other members of the gene family. Mutations in CA8 lead to CMARQ3.

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  • Sku: PSB-enz-235-5µg
  • Vendor: ProSpec-Tany
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Title

Product Details

Product Description

Recombinant Human Carbonic Anhydrase 8 is an enzyme belonging to the carbonic anhydrase family, specifically CA-VIII. With a molecular weight of approximately 30 kDa, this enzyme plays a role in catalyzing the reversible hydration of carbon dioxide to bicarbonate ions. Recombinant Human Carbonic Anhydrase 8 is commonly used in research and pharmaceutical applications due to its ability to regulate pH levels and facilitate various biochemical processes within the body.

Current Lead Time

7-14 Days

Product Specifications

Species
Human
Expression System E. coli
Purity 90% by SDS-PAGE
Activity
Not Available
Activity Assay
Animal Component Free (ACF) Yes
Molecular Weight
35.5 kDa
Structure Homodimer
Endotoxin Concentration
Not Available
Purification Method Not Available
Form
Frozen
Formulation The CA8 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 1mM DTT and 20% glycerol.

*For Research Use Only

Product Guarantee

If your product is within its expiration period, and has not performed according to expectations, fill out the sample return form. Return the unused sample frozen, with the auto generated packing slip to the address on the instructions. You will receive a full refund along with a replacement of the unused portion (inclusive of the failed test). Damages do not cover any additional costs incurred for failed experimentation. 

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MGSHMADLSF IEDTVAFPEK EEDEEEEEEG VEWGYEEGVE WGLVFPDANG EYQSPINLNS REARYDPSLL DVRLSPNYVV CRDCEVTNDG HTIQVILKSK SVLSGGPLPQ GHEFELYEVR FHWGRENQRG SEHTVNFKAF PMELHLIHWN STLFGSIDEA VGKPHGIAII ALFVQIGKEH VGLKAVTEIL QDIQYKGKSK TIPCFNPNTL LPDPLLRDYW VYEGSLTIPP CSEGVTWILF RYPLTISQLQ IEEFRRLRTH VKGAELVEGC DGILGDNFRP TQPLSDRVIR AAFQ

Storage Instruction

Reconstituted store at -20°C or -80°C.We recommend that single use aliquots are prepared to avoid freeze-thaw cycles.

Sample Prep Instruction

1. Thaw the vial on ice, spin briefly
2. Prepare single-use or stock aliquots. This stage will depend on your final application so please adapt as appropriate. All our proteins are supplied carrier protein-free. If compatible with your work and you are storing at lower concentrations (<50 ug/ml) adding carrier protein is highly advised (usually 1% w/v high purity BSA or equivalent – ensure all buffers are sterile-filtered).
3. Prepare single-use aliquots whenever possible to avoid freeze-thaw cycles which can damage the proteins and reduce bioactivity. Store aliquots at -70 °C (or -20 °C)
4. We recommend sterile filtering after dilution in media or the final working solution

References

Not Available

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CA8

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